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Anti-Mouse IL-13 Purified 500 ug

Anti-Mouse IL-13 Purified 500 ug

Quick Overview:

Anti-Mouse IL-13 Purified 500 ug

Product Code: 14-7133-85

  • Details

    The eBio13A antibody reacts with mouse IL-13. IL-13 is a cytokine produced mainly by Th2 cells, but also by antigen-primed CD8 T cells. IL-13 has a strong involvement in allergic inflammation and parasitic clearing and in cancer models has been shown to have either inhibitory or stimulatory activity depending on the tumor. In humans, IL-13 is found to play a role in isotype switching in B cells. IL-13 is implicating in down modulating macrophage activity, through the reduction of pro-inflammatory cytokines (IL-1, IL-6, IL-8, IL-10, IL-12)

  • Additional Information

    SKU 14-7133-85
    Name Anti-Mouse IL-13 Purified 500 ug
    Size 500 ug
    Product Type Functional, Purified & Recombs
    Datasheet View Datasheet
    Clone eBio13A
    Host species Rat
    Supplier eBioscience
    Applications ELISA Capture Antibody
    Species reactivity (expected) Mouse
    General Readings Miyahara, N., et al. 2004. Contribution of antigen-primed CD8+T cells to the develompent of airwary hyperresponsiveness and inflammation is associated with IL-13. J. Immunol. 172: 2539-2558.

    McKenzie AN, Li X, Largaespada DA, Sato A, Kaneda A, Zurawski SM, Doyle EL, Milatovich A, Francke U, Copeland NG, et al. Structural comparison and chromosomal localization of the human and mouse IL-13 genes.J Immunol. 1993 Jun 15;150(12):5436-44.

    Doherty TM, Kastelein R, Menon S, Andrade S, Coffman RL. Modulation of murine macrophage function by IL-13.J Immunol. 1993 Dec 15;151(12):7151-60.

    Terabe M, Matsui S, Noben-Trauth N, Chen H, Watson C, Donaldson DD, Carbone DP, Paul WE, Berzofsky JA. NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway.Nat Immunol. 2000 Dec;1(6):515-20.

    Grunig G, Warnock M, Wakil AE, Venkayya R, Brombacher F, Rennick DM, Sheppard D, Mohrs M, Donaldson DD, Locksley RM, Corry DB. Requirement for IL-13 independently of IL-4 in experimental asthma.Science. 1998 Dec 18;282(5397):2261-3.
    Storage +4C