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Anti-Mouse IL-2 Functional Grade Purified 50 ug

Anti-Mouse IL-2 Functional Grade Purified 50 ug

Quick Overview:

Anti-Mouse IL-2 Functional Grade Purified 50 ug

Product Code: 16-7022-81

  • Details

    The JES6-1A12 antibody reacts with mouse interleukin-2 (IL-2). The JES6-1A12 antibody is a neutralizing antibody. Mouse IL-2 (also known as TCGF) is a 17 kDa factor produced mainly by activated CD4+ T cells. IL-2 induces cell cycle progression of resting cells in an antigen non-specific manner and allows clonal expansion of activated T cells. IL-2 also acts on activated B cells, monocytes, NK cells, LAK cells, and on oligodendroglial cells in vitro. In addition, IL-2 plays a role in hematopoiesis, tumor surveillance and anti-inflammatory reactions, and hence is a central regulator of the immune response. Non-glycosylated IL-2 is biologically active.
  • Additional Information

    SKU 16-7022-81
    Name Anti-Mouse IL-2 Functional Grade Purified 50 ug
    Size 50 ug
    Product Type Functional, Purified & Recombs
    Datasheet View Datasheet
    Clone JES6-1A12
    Host species Rat
    Supplier eBioscience
    Applications Cytokine Neutralization, ELISA Capture Antibody, ELISPOT, Immunoprecipitation
    Species reactivity (expected) Mouse
    General Readings Abrams, J. S., M. G. Roncarolo, et al. (1992). Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunol Rev 127: 5-24.

    Sander, B., I. Hoiden, et al. (1993). Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Cytokine detection by immunoassay and intracellular immunostaining. J Immunol Methods 166(2): 201-14.
    Storage +4C