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Anti-Mouse IL-6 Functional Grade Purified 500 ug

Anti-Mouse IL-6 Functional Grade Purified 500 ug

Quick Overview:

Anti-Mouse IL-6 Functional Grade Purified 500 ug

Product Code: 16-7061-85

  • Details

    The MP5-20F3 antibody reacts with mouse interleukin-6 (IL-6). The MP5-20F3 antibody is a neutralizing antibody. Mouse IL-6 (also known as B Cell Stimulating Factor, BCSF, and BSF-2) is a 21-28 kDa factor produced by a variety of cell types, including monocytes, fibroblasts and endothelial cells. Upon stimulation, macrophages, T, B, mast, and glial cells, eosinophils, keratinocytes and granulocytes also secrete IL-6. This pleiotrophic cytokine influences the antigen-specific immune response, inflammatory response, and the development of neurons, and is a major mediator of the acute phase reaction.
  • Additional Information

    SKU 16-7061-85
    Name Anti-Mouse IL-6 Functional Grade Purified 500 ug
    Size 500 ug
    Product Type Functional, Purified & Recombs
    Datasheet View Datasheet
    Clone MP5-20F3
    Host species Rat
    Supplier eBioscience
    Applications Cytokine Neutralization, ELISA Capture Antibody, ELISPOT Capture Antibody
    Species reactivity (expected) Mouse
    General Readings Sander B, Höidén I, Andersson U, Möller E, Abrams JS. Similar frequencies and kinetics of cytokine producing cells in murine peripheral blood and spleen. Cytokine detection by immunoassay and intracellular immunostaining. J Immunol Methods. 1993 Dec 3;166(2):201-14.

    Starnes HF, Pearce M, Yim J, Abrams J, Tewari A, Zou J.Anti-IL-6 monoclonal antibodies protect against lethal Escherichia coli infection and lethal tumor necrosis factor-alpha challenge in mice. J Immunol. 1992 Mar 15;148(6):1968.
    Storage +4C