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Mouse IL-9 Single-Use ELISA RSG Standard 4 pack

Mouse IL-9 Single-Use ELISA RSG Standard 4 pack

Quick Overview:

Mouse IL-9 Single-Use ELISA RSG Standard 4 pack

Product Code: 39-8952-65

  • Details

    Interleukin 9 (IL-9) is produced by activated T helper 2 (Th2) lymphocytes. IL-9 regulates many cell types involved in classical Th2-associated asthma responses, including B and T lymphocytes, mast cells, eosinophils, and epithelial cells. The mouse IL-9 cDNA encodes a 144 amino acid precursor protein with an 18 amino acid signal peptide that is cleaved to form the mature cysteine-rich protein with a molecular mass of 14 kDa. Native mouse IL-9 is heavily glycosylated.

    Recently, TGF beta has been reported to play an important role in the differentiation of IL-17-producing T helper cells and inducible regulatory T cells by reprogramming Th2 cells to secrete IL-9, thereby driving the differentiation of Th9 cells directly.
  • Additional Information

    SKU 39-8952-65
    Name Mouse IL-9 Single-Use ELISA RSG Standard 4 pack
    Size 4 pack
    Product Type Uncoated ELISA & support pdts
    Datasheet View Datasheet
    Supplier eBioscience
    Applications ELISA Recombinant Standard
    Species reactivity (expected) Mouse
    General Readings Veldhoen M, Uyttenhove C, van Snick J, Helmby H, Westendorf A, Buer J, Martin B, Wilhelm C, Stockinger B. Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset. Nat Immunol. 2008 Dec;9(12):1341-6.

    Matsuzawa S, Sakashita K, Kinoshita T, Ito S, Yamashita T, Koike K. IL-9 enhances the growth of human mast cell progenitors under stimulation with stem cell factor. J Immunol. 2003 Apr 1;170(7):3461-7

    Nicolaides NC, Holroyd KJ, Ewart SL, Eleff SM, Kiser MB, Dragwa CR, Sullivan CD, Grasso L, Zhang LY, Messler CJ, Zhou T, Kleeberger SR, Buetow KH, Levitt RC.Interleukin 9: a candidate gene for asthma. Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):13175-80.
    Storage -80C